ea0081p500 | Thyroid | ECE2022
Gandhi Jegadeshwaran
, Mahamud Bashir
, Bell Janessa
, Ahmed Ghada
, Elshowaya Suhier
, Rehmani Hassan
, Nikookam Khash
, Mlawa Gideon
Introduction: Development and progression of cancers is multifactorial encompassing several mechanisms that aid its proliferation. One of the hallmarks of cancer progression is inhibition of the immune system. Cancer cells can activate different immune checkpoint are pathways that harbour inhibitory or stimulatory mechanisms that enabled self-tolerance and assist with immune response. Through activation of immune checkpoint pathways cancers can suppress immune response against...